Laila Nahum, PhD

Looking for Answers








Scholte LLS, Mourão MM, Pais FS, Melesina J, Robaa D, Volpini AC, Sippl W, Pierce RJ, Oliveira G, Nahum LA (2017) Evolutionary relationships among protein lysine deacetylases of parasites causing neglected diseases. Infect Genet Evol. 53:175-188. PMID: 28506839. read more

Cuesta-Astroz Y, Oliveira FS, Nahum LA, Oliveira G. (2017) Helminth secretomes reflect different lifestyles and parasitized hosts. Int J Parasitol. 47(9):529-544. PMID: 28336271. read more

Badotti F, de Oliveira FS, Garcia CF, Vaz AB, Fonseca PL, Nahum LA, Oliveira G, Góes-Neto A. (2017) DNA barcode markers for the identification of Basidiomycota (Fungi). BMC Microbiol. 17(1):42. PMID: 28228107. read more

Cuesta-Astroz Y, Scholte LL, Pais FS, Oliveira G, Nahum LA (2014) Evolutionary analysis of the cystatin family in three Schistosoma species. Front Genet. 5:206. PMID: 25071834. read more

Bonin CP, Baccarin RY, Nostell K, Nahum LA, Fossum C, de Camargo MM. (2013) Lipopolysaccharide-induced inhibition of transcription of tlr4 in vitro is reversed by dexamethasone and correlates with presence of conserved NFκB binding sites. Biochem Biophys Res Commun. 432(2):256-61. PMID: 23402753. read more

Nahum LA, Mourão MM, Oliveira G. (2012) New frontiers in schistosoma genomics and transcriptomics. J Parasitol Res. 849132. PMID: 23227308. read more

Silva LL, Marcet-Houben M, Nahum LA, Zerlotini A, Gabaldón T, Oliveira G. (2012) The Schistosoma mansoni phylome: using evolutionary genomics to gain insight into a parasite's biology. BMC Genomics. 13:617. PMID: 23148687. read more

Silva LL, Marcet-Houben M, Zerlotini A, Gabaldón T, Oliveira G, Nahum LA. (2011) Evolutionary histories of expanded peptidase families in Schistosoma mansoni. Mem Inst Oswaldo Cruz. 106(7):864-77. PMID: 22124560. read more

Avelar LG, Nahum LA, Andrade LF, Oliveira G (2011) Functional Diversity of the Schistosoma mansoni Tyrosine Kinases. J Signal Transduct. 603290. PMID: 21776387. read more

Andrade LF, Nahum LA, Avelar LGA, Silva LL, Zerlotini A, Ruiz JC, Oliveira O (2011) Eukaryotic protein kinases (ePKs) of the helminth parasite Schistosoma mansoni. BMC Genomics 12(1):215. PMID: 21548963. read more

Oliveira SB, Ibraim IC, Tadei WP, Ruiz JC, Nahum LA, Brito CFA, Moreira LA. (2011) Identification of a fibrinogen-related protein (FBN9) gene in neotropical anopheline mosquitoes. Malaria Journal. 10:21. PMID : 21288344. read more

Nahum LA, Goswami S, Serres MH. (2009) Protein families reflect the metabolic diversity of organisms and provide support for functional prediction. Physiol Genomics. 38(3):250-60. PMID: 19491149. read more

Nahum LA, Reynolds MT, Wang ZO, Faith JJ, Jonna R, Jiang ZJ, Meyer TJ, Pollock DD. (2006) EGenBio: a data management system for evolutionary genomics and biodiversity. BMC Bioinformatics. 7 Suppl 2:S7. PMID: 17118150. read more

Camargo MM, Nahum LA. (2005) Adapting to a changing world: RAG genomics and evolution. Hum Genomics. 2(2):132-7. PMID: 16004728. read more

Nahum LA, Pereira SL, Fernandes, F.M.C., Matioli, S.R. and Wajntal A (2003) Diversification of Ramphastinae (Aves, Ramphastidae) prior to the Cretaceous/Tertiary boundary as shown by molecular clock of mtDNA sequences. Genetics and Molecular Biology 26(4):411-418. read more

Serres MH, Gopal S, Nahum LA, Liang P, Gaasterland T, Riley M. (2001) A functional update of the Escherichia coli K-12 genome. Genome Biol. 2(9):RESEARCH0035. PMID: 11574054. read more

Nahum LA, Riley M. (2001) Divergence of function in sequence-related groups of Escherichia coli proteins. Genome Res. 11(8):1375-81. PMID: 11483578. read more

Miyaki CY, Griffiths, R., Orr, K., Nahum LA, Pereira SL and Wajntal A (1998) Sex identification of parrots, toucans, and curassows by PCR: perspectives for wild and captive population studies. Zoo Biology 17:415-423. read more

Book chapters

Nahum LA, Ruiz JC (2015) Filogenômica. In: Leandro Marcio Moreira. (Org.). Ciências genômicas: fundamentos e aplicações. 1ed. Ribeirão Preto: Sociedade Brasileira de Genética. p. 117-142.  read more

Nahum LA (2012) Genome Evolution. In: Molecular Biology and Evolution. S.R. Matioli & F.M.C. Fernandes editors. 2nd edition. Holos Editora, Ribeirão Preto, SP – Brazil. p. 91-104.  read more

Nahum LA and Pereira SL (2008) Phylogenomics, Protein Family Evolution, and the Tree of Life: An Integrated Approach between Molecular Evolution and Computational Intelligence. In: Smolinski TG, Milanova MG, Hassanien A-E (eds), Studies in Computational Intelligence (SCI) 122, 259–279. Springer-Verlag Berlin Heidelberg. read more

Nahum LA (2001) Genome Evolution. In: Molecular Biology and Evolution. S.R. Matioli editor. 1st edition. Holos Editora, Ribeirão Preto, SP – Brazil. p. 82-96. read more


Research Insights

Mitochondrial genomes of plants are much larger than those of mammals and often contain conserved open reading frames (ORFs) of unknown function. Here, we show that one of these conserv... read more


Miniature tomato, S. lycopersicum cultivar Micro- Tom, was grown as described previously.22 Roots were harvested 5 weeks after germination. Hypocotyl and cotyledon were harvested 3 weeks after germination. Third leaves were harvested 3 weeks after germ.... read more


Initial gene discovery efforts through analysis of genome sequences and identification and characterization of expressed RNAs have revealed that only a relatively small portion of the genome is transcribed into protein coding mRNAs ... read more


Comparative genetics and genomics use knowledge from different species to define important evolutionary relationships, an important aspect of which is the physical and genetic synteny (two or more homologous loci found on a single chromosome) and ... read more


Centro de Pesquisas Ren Rachou
Marine Biological Laboratory
Centro de Excelência em Bioinformática
National Institutes of Health
Universidade Federal de Minas Gerais
PUC Minas

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